Dose-response Relationship of Lymphocyte Chromosome Aberrations in Locally Irradiated Persons
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چکیده
منابع مشابه
Chromosome aberrations in human lymphocytes irradiated with heavy ions
Because of the increasing use of heavy ions in cancer therapy and for the planning of manned space travels, a realistic estimate of the health risks associated with particle exposure is indispensable. The standard method to quantify the exposed dose and to assess the health risks of radiation is the analysis of chromosome aberrations in peripheral blood lymphocytes at the first post-irradiation...
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Chromosome examinations were made both in cultured peripheral lymphocytes and in freshly aspirated bone marrow cells of 6 persons accidentally exposed to gamma rays from an 192Ir. Samplings of peripheral blood for the chromosome analysis were repeated mostly at weekly in tervals during the hospitalization beginning on 10-11 days after the initial exposure, and at more prolonged intervals after ...
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Modern radiation cytogenetics has adopted the principle that DNA molecule as an essential biological substrate is the most important target of ionizing radiation. This action may result in delicate lesions of the hereditary material that may be manifested in the form of structural chromosomal aberrations. This study present results of years of cytogenetic studies of chromosomal aberrations in i...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 1974
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.15.189